All-Northern 10 Athletic Conference Softball 2021
| First team | ||
| Player | School | Yr |
| Caleigh Rister | Bucyrus | 12 |
| Jade Torres | Bucyrus | 12 |
| Lauren Frietchen | Col. Crawford | 10 |
| Alivia Studer | Col. Crawford | 11 |
| Paityn Clouse | Mohawk | 12 |
| Aubrie Harper | Mohawk | 12 |
| Bailey Sheets | Mohawk | 10 |
| Olivia VanBuskirk | Ridgedale | 12 |
| Jessica Bowerman | Seneca East | 12 |
| Jenna Clary | Upper Sandusky | 12 |
| Hannah Plymale | Upper Sandusky | 10 |
| Brooke Swavel | Upper Sandusky | 11 |
| Player of the year | ||
| Caleigh Rister, Bucyrus | ||
| Coach of the year | ||
| Jerry Hargis, Bucyrus | ||
| Second team | ||
| Player | School | Yr |
| Lexia Clinger | Carey | 11 |
| Hunter Hart | Carey | 12 |
| Mary Racheter | Carey | 12 |
| Jostyn Gallant | Col. Crawford | 10 |
| Kaylyn Risner | Col. Crawford | 11 |
| Allison Weithman | Col. Crawford | 9 |
| Victoria Phillips | Mohawk | 11 |
| Lily Ruth | Ridgedale | 9 |
| Olivia Gier | Upper Sandusky | 10 |
| Jenna Kurtz | Upper Sandusky | 11 |
| Madalyn Johnson | Wynford | 11 |
| Adrienne Whitmeyer | Wynford | 11 |
| Honorable mention | ||
| Player | School | Yr |
| Emma Lane | Buckeye Central | 11 |
| Ashley Davis | Bucyrus | 11 |
| Carmen Conigy | Carey | 11 |
| Harley Thomas | Col. Crawford | 10 |
| Marah Gillig | Mohawk | 12 |
| Kennedi Ferguson | Ridgedale | 10 |
| Lauren Bogner | Seneca East | 12 |
| Jade Holman | Upper Sandusky | 12 |
| Kearston Hulsmeyer | Wynford | 12 |